Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614233 | 0.87 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| SCHEMBL8612683 | 0.77 | MAPT (0.46) | HSP90AA1HSP90AB1MAPTGPR84NSD2 | |
| SCHEMBL8614235 | 0.74 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| SCHEMBL482437 | 0.73 | DNMT1 (0.40) | L3MBTL1MAPTMAPK1TDP1GPR84 | |
| SCHEMBL9950485 | 0.73 | NSD2 (0.50) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| SCHEMBL8611708 | 0.71 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL29492626 | 0.71 | NSD2 (0.51) | HSP90AA1HSP90AB1MAPTNSD2OPRM1 | |
| SCHEMBL29360295 | 0.70 | NSD2 (0.54) | HSP90AA1HSP90AB1MAPTTDP1NSD2 | |
| SCHEMBL6403846 | 0.70 | NSD2 (0.54) | HSP90AA1HSP90AB1MAPTNSD2OPRM1 | |
| SCHEMBL214870 | 0.70 | NSD2 (0.54) | HSP90AA1HSP90AB1MAPTTDP1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |