Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585116 | 0.80 | ALDH1A1 (0.44) | DNMT1WDR5ALDH1A1TDP1TSHR | |
| SCHEMBL1925928 | 0.80 | ALDH1A1 (0.44) | DNMT1WDR5ALDH1A1TDP1TSHR | |
| SCHEMBL30810802 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRHSD17B10CYP2A6 | |
| SCHEMBL5531704 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRHSD17B10CYP2A6 | |
| SCHEMBL8614233 | 0.77 | HSP90AA1 (0.39) | ALDH1A1TDP1HSD17B10MEN1KMT2A | |
| SCHEMBL28386630 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRHSD17B10CYP2A6 | |
| SCHEMBL1304679 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRHSD17B10CYP2A6 | |
| Hydrochloric Acid SCHEMBL28378153 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1HSD17B10CYP2A6HPGD | |
| SCHEMBL2824075 | 0.76 | HSD17B10 (0.44) | DNMT1WDR5ALDH1A1TDP1TSHR | |
| SCHEMBL29489771 | 0.76 | HSD17B10 (0.44) | DNMT1WDR5ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183437-B2 | Method for preparing three types of benzidine compounds in a specific ratio | LABELTEK INC. (TW) | 2007-02-27 | — | — | US | claimed |
| US-20050080292-A1 | Method for preparing three types of benzidine compounds in a specific ratio | LABELTEK INC. (TW) | 2005-04-14 | — | — | US | claimed |
| US-20210318619-A1 | COMPOSITION, METHOD OF PRODUCING SUBSTRATE, METHOD OF FORMING PATTERN, AND METHOD OF FORMING REVERSE PATTERN | JSR CORPORATION (JP) | 2021-10-14 | — | — | US | disclosed |
| US-8604030-B2 | Fused piperidine compound and pharmaceutical containing same | KOWA COMPANY, LTD. (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120108581-A1 | FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL CONTAINING SAME | KOWA COMPANY, LTD (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2412710-A1 | FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL AGENT COMPRISING SAME | Kowa Company, Ltd. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1847535-A1 | 1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |
| US-7183437-B2 | Method for preparing three types of benzidine compounds in a specific ratio | LABELTEK INC. (TW) | 2007-02-27 | — | — | US | disclosed |
| EP-1229065-B1 | Process for the preparation of a polyesteramide | COUNCIL SCIENT IND RES (IN) | 2005-06-08 | — | — | EP | disclosed |
| US-20050080292-A1 | Method for preparing three types of benzidine compounds in a specific ratio | LABELTEK INC. (TW) | 2005-04-14 | — | — | US | disclosed |
| EP-1229065-A1 | Process for the preparation of a polyesteramide | Council of Scientific and Industrial Research (IN) | 2002-08-07 | — | — | EP | disclosed |
| US-6410681-B1 | ALTERNATING POLYESTER, POLYAMIDE UNITS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | TPH1, HTR1D, HTR1B | DNMT1 2081/4885TNF 4686/4885WDR5 492/4885 |
| US-20050080292-A1 | Method for preparing three types of benzidine compounds in a specific ratio | DRD4, DRD5, DDT | DNMT1 848/4885TNF 4053/4885WDR5 1788/4885 |
| US-20120108581-A1 | FUSED PIPERIDINE COMPOUND AND PHARMACEUTICAL CONTAINING SAME | EPOR, JAK2, HBZ | DNMT1 2572/4885TNF 1162/4885WDR5 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.