Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614230 | 0.89 | ACMSD (0.35) | HSP90AA1HSP90AB1L3MBTL1MAPTMAPK1 | |
| SCHEMBL8614233 | 0.87 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| SCHEMBL8612730 | 0.83 | MAPT (0.41) | HSP90AA1HSP90AB1MAPTGPR84MEN1 | |
| SCHEMBL8611053 | 0.74 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| SCHEMBL8612727 | 0.71 | MAPT (0.44) | HSP90AA1HSP90AB1MAPTGPR84MEN1 | |
| SCHEMBL10434030 | 0.70 | DHFR (0.40) | L3MBTL1MAPTMAPK1TDP1MEN1 | |
| SCHEMBL8613188 | 0.69 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1L3MBTL1MAPTTHRB | |
| SCHEMBL6403846 | 0.69 | NSD2 (0.54) | HSP90AA1HSP90AB1MAPTCYP2C19CYP2C9 | |
| SCHEMBL29489770 | 0.69 | HSD17B10 (0.44) | L3MBTL1MAPTTHRBMAPK1TDP1 | |
| SCHEMBL29489771 | 0.69 | HSD17B10 (0.44) | L3MBTL1MAPTTHRBMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |