SCHEMBL8611208

SCHEMBL8611208

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nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PREP P48147 1/20 0.49
FAP Q12884 1/20 0.49
XIAP P98170 2/20 0.48
DPP4 P27487 1/20 0.44
DPP8 Q6V1X1 1/20 0.44
DPP9 Q86TI2 1/20 0.44
ELANE P08246 12/20 0.42
MLX Q9UH92 1/20 0.42
CMA1 P23946 1/20 0.41
ACE2 Q9BYF1 1/20 0.40
CALCRL Q16602 1/20 0.39
CTSG P08311 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961236 1.00 PREP (0.49) PREPFAPXIAPDPP4DPP8
SCHEMBL8922480 1.00 PREP (0.49) PREPFAPXIAPDPP4DPP8
SCHEMBL30582861 0.90 XIAP (0.55) XIAPELANEMLXCMA1CALCRL
SCHEMBL8922544 0.89 XIAP (0.47) XIAPELANEMLXCMA1CTSG
SCHEMBL8611726 0.89 XIAP (0.47) XIAPELANEMLXCMA1CTSG
SCHEMBL8613939 0.87 XIAP (0.57) PREPFAPXIAPELANEMLX
SCHEMBL8920341 0.87 XIAP (0.57) PREPFAPXIAPELANEMLX
SCHEMBL30216504 0.87 XIAP (0.52) XIAPELANEMLXCMA1CALCRL
SCHEMBL9622786 0.86 PREP (0.49) PREPFAPXIAPDPP4DPP8
SCHEMBL8920472 0.86 CMA1 (0.53) XIAPELANECMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287106-A1 Method for Producing Fluorescent Probe Library Using Solid-Phase Extraction and Method of Measuring Enzyme Activity Using Same RIKEN (JP) 2024-08-29 US disclosed
EP-4353731-A1 METHOD FOR PRODUCING FLUORESCENT PROBE LIBRARY USING SOLID-PHASE EXTRACTION AND METHOD OF MEASURING ENZYME ACTIVITY USING SAME The University of Tokyo (JP) 2024-04-17 EP disclosed
WO-2022260135-A1 METHOD FOR PRODUCING FLUORESCENT PROBE LIBRARY USING SOLID-PHASE EXTRACTION AND METHOD OF MEASURING ENZYME ACTIVITY USING SAME 国立大学法人 東京大学 2022-12-15 WO disclosed
EP-0693080-B1 NEW GLUCOCORTICOIDS SCHERING AG (DE) 1998-04-22 EP disclosed
US-5616573-A Glucocorticoids SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-01 US disclosed
EP-0693080-A1 NEW GLUCOCORTICOIDS SCHERING AKTIENGESELLSCHAFT (DE) 1996-01-24 EP disclosed
WO-1994022898-A1 NEW GLUCOCORTICOIDS SCHERING AKTIENGESELLSCHAFT (DE) 1994-10-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287106-A1 Method for Producing Fluorescent Probe Library Using Solid-Phase Extraction and Method of Measuring Enzyme Activity Using Same NOTUM, GUSB, RNGTT PREP 26/4885FAP 267/4885XIAP 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.