Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 17/20 | 0.38 |
| ▸ | CTSK | P43235 | 15/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9544252 | 0.78 | CTSK (0.37) | MEN1KMT2ACTSSCTSKDGAT1 | |
| SCHEMBL9179185 | 0.78 | CTSK (0.37) | MEN1KMT2ACTSSCTSKDGAT1 | |
| SCHEMBL16268583 | 0.77 | MEN1 (0.51) | MEN1KMT2ACTSSCTSKCTSL | |
| SCHEMBL28534490 | 0.76 | DGAT1 (0.45) | MEN1KMT2ACTSSCTSKDGAT1 | |
| SCHEMBL28323881 | 0.75 | DGAT1 (0.39) | MEN1KMT2ACTSSCTSKDGAT1 | |
| Ammonia Solution, Strong SCHEMBL28163211 | 0.74 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL18248046 | 0.72 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL18248114 | 0.72 | DGAT1 (0.37) | MEN1KMT2ACTSSCTSKCTSL | |
| SCHEMBL17498185 | 0.71 | MEN1 (0.41) | MEN1KMT2ACTSSCTSKCTSL | |
| SCHEMBL16268603 | 0.69 | MEN1 (0.39) | MEN1KMT2ACTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833654-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-1 RECEPTOR | Affymax Technologies N.V. (GB) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996039165-A1 | PEPTIDES AND COMPOUNDS THAT BIND TO THE IL-1 RECEPTOR | AFFYMAX TECHNOLOGIES N.V. (GB) | 1996-12-12 | — | — | WO | disclosed |