⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15517784 | 1.00 | — | — | |
| SCHEMBL13800899 | 1.00 | — | — | |
| SCHEMBL31110593 | 1.00 | — | — | |
| SCHEMBL3246578 | 1.00 | — | — | |
| SCHEMBL23522673 | 0.95 | THRB (0.38) | — | |
| SCHEMBL13509339 | 0.95 | THRB (0.38) | — | |
| SCHEMBL23867729 | 0.95 | THRB (0.38) | — | |
| SCHEMBL22030605 | 0.95 | THRB (0.38) | — | |
| SCHEMBL12262915 | 0.95 | THRB (0.38) | — | |
| SCHEMBL29253 | 0.95 | THRB (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006024-A1 | HETEROCYCLIC AMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
| US-9512162-B2 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites and oligonucleotides | ASED, LLC (US) | 2016-12-06 | — | — | US | disclosed |
| US-9493773-B2 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2016-11-15 | — | — | US | disclosed |
| US-9365607-B1 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150252071-A1 | Synthesis of Deuterated Ribo Nucleosides, N-Protected Phosphoramidites and Oligonucleotides | ASED, LLC | 2015-09-10 | — | — | US | disclosed |
| EP-2882768-A2 | SYNTHESIS OF DEUTERATED RIBO NUCLEOSIDES, N-PROTECTED PHOSPHORAMIDITES, AND OLIGONUCLEOTIDES | Ased, LLC (US) | 2015-06-17 | — | — | EP | disclosed |
| EP-2882769-A2 | SYNTHESIS OF DEUTERATED RIBO NUCLEOSIDES, N-PROTECTED PHOSPHORAMIDITES, AND OLIGONUCLEOTIDES | Ased, LLC (US) | 2015-06-17 | — | — | EP | disclosed |
| US-9045521-B2 | Synthesis of deuterated ribo nucleosides N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2015-06-02 | — | — | US | disclosed |
| US-20150119565-A1 | SYNTHESIS OF DEUTERATED RIBO NUCLEOSIDES, N-PROTECTED PHOSPHORAMIDITES, AND OLIGONUCLEOTIDES | ASED, LLC | 2015-04-30 | — | — | US | disclosed |
| US-8859754-B2 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC (US) | 2014-10-14 | — | — | US | disclosed |
| US-20140039178-A1 | Synthesis of deuterated ribo nucleosides N-protected phosphoramidites, and oligonucleotides | ASED, LLC | 2014-02-06 | — | — | US | disclosed |
| WO-2014022566-A2 | SYNTHESIS OF DEUTERATED RIBO NUCLEOSIDES, N-PROTECTED PHOSPHORAMIDITES, AND OLIGONUCLEOTIDES | ASED, LLC (US) | 2014-02-06 | — | — | WO | disclosed |
| WO-2014022563-A2 | SYNTHESIS OF DEUTERATED RIBO NUCLEOSIDES, N-PROTECTED PHOSPHORAMIDITES, AND OLIGONUCLEOTIDES | ASED, LLC (US) | 2014-02-06 | — | — | WO | disclosed |
| US-20140039175-A1 | Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides | ASED, LLC | 2014-02-06 | — | — | US | disclosed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | disclosed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | disclosed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | disclosed |