SCHEMBL29253

SCHEMBL29253

COC1OCC(O)C(O)C1O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TYR P14679 5/20 0.35
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
CA1 P00915 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.31
M6PR P20645 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14817881 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL12262915 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL5982317 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL12205501 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL23867729 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL13509339 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL23522673 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL4921744 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL23549931 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR
SCHEMBL22030605 1.00 THRB (0.38) THRBLMNAMEN1KMT2ATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626460-A1 AGENTS, COMPOSITIONS AND METHODS FOR MODULATING IMMUNITY The University of Queensland (AU) 2025-10-08 EP disclosed
US-20250275993-A1 GLYCOSYLATION INHIBITORS AS THERAPEUTICS FOR STROKE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-04 US disclosed
WO-2024113009-A1 AGENTS, COMPOSITIONS AND METHODS FOR MODULATING IMMUNITY THE UNIVERSITY OF QUEENSLAND (AU) 2024-06-06 WO disclosed
CN-113135966-B Bicyclic derivatives of heterocyclic glucoside and preparation method and application thereof 华润双鹤药业股份有限公司 2022-12-16 CN disclosed
US-20210188890-A1 SELECTIVE VALORIZATION OF BIOMASS SUGARS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2021-06-24 US disclosed
US-20210121383-A1 COMPOSITION FOR ANTI-AGING MORINAGA MILK INDUSTRY CO., LTD. (JP) 2021-04-29 US disclosed
EP-3156058-B1 ANTI-TUMOR PHARMACEUTICAL APPLICATION OF PENTACYCLIC TRITERPENE SAPONIN COMPOUNDS OF SZECHUAN MELANDIUM ROOT WANG XUEYONG (CN) 2020-05-27 EP disclosed
US-10570164-B2 Steviol glycosides, their compositions and their purification THE COCA-COLA COMPANY (US) 2020-02-25 US disclosed
CN-106083943-B Glucopyranosyl derivative and preparation method and application thereof 广东东阳光药业有限公司 2020-01-14 CN disclosed
EP-3140314-B1 A NON-CALORIC SWEETENER CONAGEN INC (US) 2019-07-31 EP disclosed
US-20100311673-A1 SULFANYL-TETRAHYDROPYRAN-BASED COMPOUNDS AND METHODS OF THEIR USE OXFORD FINANCE LLC, AS COLLATERAL AGENT 2010-12-09 US disclosed
US-7846945-B2 Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their use LEXICON PHARMACEUTICALS, INC. (US) 2010-12-07 US disclosed
US-7781577-B2 2-[4-Chloro-3-(4-hydroxy-benzyl)-phenyl]-6-methoxy-tetrahydro-pyran-3,4,5-triol; 2-[4-Chloro-3-(4-ethoxy-benzyl)-phenyl]-3,4,5-trihydroxy-piperidine-1-carboxylic acid methyl ester; (2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-methoxytetrahydro-2H-thiopyran-3,4,5-triol; antidibetic, antiobesity agents LEXICON PHARMACEUTICALS, INC. (US) 2010-08-24 US disclosed
US-20100028559-A1 Method for functionalizing materials and devices comprising such materials THE STATE OF OREGON ACTING BY AND THROUGH STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND 2010-02-04 US disclosed
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME KAO CORPORATION (JP) 2009-04-16 US disclosed
WO-2008156510-A2 METHOD FOR FUNCTIONALIZING MATERIALS AND DEVICES COMPRISING SUCH MATERIALS STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2008-12-24 WO disclosed
US-20080221164-A1 Inhibitors of Sodium Glucose Co-Transporter 2 and Methods of Their Use OXFORD FINANCE LLC, AS COLLATERAL AGENT 2008-09-11 US disclosed
US-20080113922-A1 INHIBITORS OF SODIUM GLUCOSE CO-TRANSPORTER 2 AND METHODS OF THEIR USE OXFORD FINANCE LLC, AS COLLATERAL AGENT 2008-05-15 US disclosed
WO-2007141513-A1 USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY NOVABIOTICS LIMITED (GB) 2007-12-13 WO disclosed
EP-1730159-B1 DERIVATIVES OF GENKWANIN AND SAKURANETIN, COSMETIC AND THERAPEUTIC USE THEREOF AND PREPARATION METHOD OF SAME PROST MICHEL (FR) 2007-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113922-A1 INHIBITORS OF SODIUM GLUCOSE CO-TRANSPORTER 2 AND METHODS OF THEIR USE SLC2A1, SLC2A2, SLC5A2 THRB 815/4885LMNA 3320/4885MEN1 4606/4885
US-20100028559-A1 Method for functionalizing materials and devices comprising such materials ALDH1A2, LGALS3, LGALS3BP THRB 4158/4885LMNA 879/4885MEN1 3122/4885
US-20210121383-A1 COMPOSITION FOR ANTI-AGING GLA, GLB1, LIMS1 THRB 3995/4885LMNA 613/4885MEN1 4528/4885
US-10570164-B2 Steviol glycosides, their compositions and their purification TAS2R7, TAS2R31, TAS2R40 THRB 3858/4885LMNA 4183/4885MEN1 1223/4885
US-20100311673-A1 SULFANYL-TETRAHYDROPYRAN-BASED COMPOUNDS AND METHODS OF THEIR USE GPR119, FABP4, LIPC THRB 477/4885LMNA 3376/4885MEN1 4167/4885
US-20080221164-A1 Inhibitors of Sodium Glucose Co-Transporter 2 and Methods of Their Use SLC2A1, SLC2A2, SLC5A2 THRB 815/4885LMNA 3320/4885MEN1 4606/4885
US-20090098172-A1 SURFACTANT, AND EMULSION COSMETIC AND LIPOSOME EACH CONTAINING THE SAME TREH, LIPA, SGMS1 THRB 2803/4885LMNA 2591/4885MEN1 3332/4885
US-20210188890-A1 SELECTIVE VALORIZATION OF BIOMASS SUGARS GALE, FBP1, GNE THRB 2056/4885LMNA 4488/4885MEN1 2625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.