Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462625 | 0.96 | GSTP1 (0.58) | GSTP1GRM5FFAR1MAOBLMNA | |
| SCHEMBL8619308 | 0.94 | GSTP1 (0.56) | GSTP1GRM5FFAR1MAOBLMNA | |
| SCHEMBL8612148 | 0.91 | GSTP1 (0.54) | GSTP1GRM5FFAR1MAOBLMNA | |
| SCHEMBL8612975 | 0.89 | GSTP1 (0.51) | GSTP1GRM5FFAR1MAOBMAPT | |
| SCHEMBL8612830 | 0.88 | GSTP1 (0.50) | GSTP1GRM5FFAR1MAOBLMNA | |
| SCHEMBL8616573 | 0.86 | KDM1A (0.46) | GSTP1GRM5SLC6A2SLC6A3MAPT | |
| SCHEMBL8613877 | 0.86 | ALOX5 (0.51) | GSTP1GRM5FFAR1MAOBMAOA | |
| SCHEMBL8612218 | 0.85 | FFAR1 (0.47) | GSTP1GRM5FFAR1MAOBMAOA | |
| SCHEMBL8616565 | 0.84 | ALOX5 (0.53) | GSTP1GRM5FFAR1MAOBMAOA | |
| SCHEMBL8617314 | 0.84 | FFAR1 (0.49) | GSTP1GRM5FFAR1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |