Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436536 | 0.93 | MEN1 (0.66) | MEN1KMT2APTGER4PTGER3PTGER2 | |
| SCHEMBL28436540 | 0.93 | MEN1 (0.66) | MEN1KMT2APTGER4PTGER3PTGER2 | |
| SCHEMBL15105021 | 0.82 | TRPA1 (0.63) | MEN1KMT2APTGER4PTGER3PTGER2 | |
| SCHEMBL3869325 | 0.82 | TRPA1 (0.63) | MEN1KMT2APTGER4PTGER3PTGER2 | |
| SCHEMBL827239 | 0.82 | LMNA (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL112366 | 0.82 | LMNA (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL112365 | 0.82 | LMNA (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL14764012 | 0.82 | LMNA (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL1532460 | 0.82 | LMNA (0.65) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL16689985 | 0.81 | LMNA (0.75) | MEN1KMT2ALMNATDP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833812-A1 | CHEMICAL COMPOUNDS AND METHODS OF PRODUCTION THEREOF | ZYLEPSIS LIMITED (GB) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000851-A1 | CHEMICAL COMPOUNDS AND METHODS OF PRODUCTION THEREOF | ZYLEPSIS LIMITED (GB) | 1997-01-09 | — | — | WO | disclosed |