Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GALR2 | O43603 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6354726 | 0.92 | SLC9A1 (0.59) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL10759973 | 0.92 | SLC9A1 (0.63) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL29386167 | 0.92 | SLC9A1 (0.63) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL27941949 | 0.89 | SLC9A1 (0.60) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL2972082 | 0.89 | SLC9A1 (0.60) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL6816581 | 0.89 | CXCR2 (0.63) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL27796244 | 0.88 | SLC9A1 (0.56) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL30296307 | 0.87 | SLC9A1 (0.55) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL6200886 | 0.87 | SLC9A1 (0.62) | SLC9A1MAPTNPSR1ALDH1A1LMNA | |
| SCHEMBL8513944 | 0.86 | MAPT (0.55) | SLC9A1MAPTNPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |