SCHEMBL8513944

SCHEMBL8513944

CC(=O)Nc1cc(Cl)c(Cl)cc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.55
▸ NPSR1 Q6W5P4 2/20 0.55
▸ SLC9A1 P19634 1/20 0.53
▸ HTT P42858 2/20 0.53
▸ KMT2A Q03164 3/20 0.49
▸ PDE7A Q13946 1/20 0.49
▸ POLB P06746 2/20 0.48
▸ GALR2 O43603 1/20 0.48
▸ MITF O75030 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ HSP90AA1 P07900 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ XBP1 P17861 1/20 0.48
▸ CCR6 P51684 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ PKM P14618 3/20 0.46
▸ ALDH3A1 P30838 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.43
▸ CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27796244 0.92 SLC9A1 (0.56) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL863876 0.89 SLC9A1 (0.53) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL405563 0.89 MAPT (0.51) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL6354726 0.88 SLC9A1 (0.59) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL11252461 0.87 MAPT (0.50) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL21989034 0.87 SLC9A1 (0.52) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL6167927 0.87 MAPT (0.50) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL8611539 0.86 SLC9A1 (0.64) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL3915677 0.86 SLC9A1 (0.51) MAPTNPSR1SLC9A1HTTKMT2A
SCHEMBL3915656 0.85 SLC9A1 (0.56) MAPTNPSR1SLC9A1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018091978-A1 A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE AMOGH CHEMICALS PVT. LTD (IN) 2018-05-24 — — WO claimed
US-20130303781-A1 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2013-11-14 — — US claimed
EP-2642995-A2 PROCESS FOR PREPARATION OF TRICLABENDAZOLE Sequent Scientific Ltd. (IN) 2013-10-02 — — EP claimed
WO-2012070068-A2 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2012-05-31 — — WO claimed
WO-2018091978-A1 A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE AMOGH CHEMICALS PVT. LTD (IN) 2018-05-24 — — WO disclosed
WO-2018091978-A1 A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE AMOGH CHEMICALS PVT. LTD (IN) 2018-05-24 — — WO disclosed
WO-2018091978-A1 A PROCESS FOR THE PREPARATION OF 2-NITRO-4,5- DICHLOROACETANILIDE AMOGH CHEMICALS PVT. LTD (IN) 2018-05-24 — — WO disclosed
US-20130303781-A1 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2013-11-14 — — US disclosed
US-20130303781-A1 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2013-11-14 — — US disclosed
US-20130303781-A1 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2013-11-14 — — US disclosed
US-20130303781-A1 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2013-11-14 — — US disclosed
EP-2642995-A2 PROCESS FOR PREPARATION OF TRICLABENDAZOLE Sequent Scientific Ltd. (IN) 2013-10-02 — — EP disclosed
EP-2642995-A2 PROCESS FOR PREPARATION OF TRICLABENDAZOLE Sequent Scientific Ltd. (IN) 2013-10-02 — — EP disclosed
WO-2012070068-A3 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2012-07-19 — — WO disclosed
WO-2012070068-A2 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2012-05-31 — — WO disclosed
WO-2012070068-A2 PROCESS FOR PREPARATION OF TRICLABENDAZOLE SEQUENT SCIENTIFIC LIMITED (IN) 2012-05-31 — — WO disclosed
US-7763616-B2 Piperazine-piperidines with CXCR3 antagonist activity SCHERING CORPORATION (US) 2010-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303781-A1 PROCESS FOR PREPARATION OF TRICLABENDAZOLE NIT2, CA3, TET3 MAPT 4414/4885NPSR1 2807/4885SLC9A1 946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback