Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611585 | 0.92 | ADRA2A (0.50) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL15512522 | 0.91 | MAPT (0.46) | ADRA2AADRA1AMAPTALDH1A1DGKA | |
| SCHEMBL21694923 | 0.89 | MAPT (0.49) | MAPTALDH1A1DGKALMNATSHR | |
| SCHEMBL11077835 | 0.89 | ADRA2A (0.47) | ADRA2AADRA1AMAPTBLMKDM6B | |
| SCHEMBL27216289 | 0.87 | KDM4C (0.41) | ADRA2AADRA1AMAPTBLMKDM6B | |
| SCHEMBL19817290 | 0.86 | MAPT (0.52) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL30173728 | 0.86 | ADRA2A (0.43) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL20775329 | 0.86 | MAPT (0.47) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL19815617 | 0.86 | ADRA2A (0.48) | ADRA2AADRA1AMAPTBLMHTR2C | |
| SCHEMBL536561 | 0.86 | MAPT (0.45) | MAPTALDH1A1DGKANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792875-A | Catalytic production of butyrolactone or tetrahydrofuran | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-08-11 | — | — | US | disclosed |