Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22028559 | 0.92 | ADRA2A (0.54) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL8611593 | 0.89 | ADRA2A (0.44) | ADRA2AADRA1AMAPTBLMKDM2A | |
| SCHEMBL1258235 | 0.89 | MAPT (0.47) | ADRA2AADRA1AMAPTALDH1A1LMNA | |
| SCHEMBL8679685 | 0.87 | MAPT (0.50) | MAPTALDH1A1LMNADGKA | |
| SCHEMBL963696 | 0.87 | MAPT (0.50) | MAPTALDH1A1LMNADGKA | |
| SCHEMBL13575623 | 0.86 | CYP19A1 (0.45) | ADRA2AADRA1AMAPTBLMKDM2A | |
| SCHEMBL1743791 | 0.84 | ADRA2A (0.42) | ADRA2AADRA1AMAPTBLMKDM2A | |
| SCHEMBL28687972 | 0.83 | LMNA (0.40) | ADRA2AADRA1AMAPTBLMKDM2A | |
| SCHEMBL23926237 | 0.83 | MAPT (0.48) | ADRA2AADRA1AMAPTBLMALDH1A1 | |
| SCHEMBL12076454 | 0.83 | MAPT (0.53) | ADRA2AADRA1AMAPTBLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104727-A1 | Pyridinyl-substituted benzimidazoles and quinoxalines | THE UPJOHN COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |
| US-4430502-A | Pyridinyl substituted benzimidazoles and quinoxalines | THE UPJOHN COMPANY (US) | 1984-02-07 | — | — | US | disclosed |