Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | PDE9A | O76083 | 2/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486477 | 0.89 | GRIA1 (0.58) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL3588054 | 0.81 | PDE9A (0.52) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8610630 | 0.81 | GRIK1 (0.53) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8117343 | 0.80 | MEN1 (0.47) | GRIA1GRIA2GRIA3GRIA4PDE5A | |
| SCHEMBL7478166 | 0.80 | PDE5A (0.50) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL9544064 | 0.80 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4PDE5A | |
| SCHEMBL8612182 | 0.80 | GRIA1 (0.69) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL3593767 | 0.79 | PDE9A (0.50) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL8191089 | 0.79 | GRIK1 (0.55) | GRIK1GRIK2GRIK3GRIK4GRIK5 | |
| SCHEMBL24335140 | 0.78 | PDE5A (0.48) | GRIK1GRIK2GRIK3GRIK4GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852017-A | 2,3(1H,4H)-quinoxalinediones | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| US-5714489-A | 2,3(1H,4H)quinoxalinedione | BASF AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |