Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 1.00 |
| ▸ | DRD2 | P14416 | 9/20 | 1.00 |
| ▸ | DRD3 | P35462 | 9/20 | 1.00 |
| ▸ | HTR6 | P50406 | 6/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485880 | 0.84 | DRD2 (0.73) | DRD4DRD2DRD3HTR6BCHE | |
| SCHEMBL8487697 | 0.81 | DRD2 (0.67) | DRD4DRD2DRD3KMT2A | |
| SCHEMBL1142167 | 0.79 | DRD2 (0.65) | DRD4DRD2DRD3 | |
| SCHEMBL30481265 | 0.79 | DRD2 (0.65) | DRD4DRD2DRD3 | |
| SCHEMBL7206828 | 0.79 | DRD2 (1.00) | DRD4DRD2DRD3HTR6 | |
| SCHEMBL11701339 | 0.77 | DRD4 (0.77) | DRD4DRD2DRD3HTR6KDM4E | |
| SCHEMBL10668370 | 0.76 | DRD2 (0.62) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL8120489 | 0.75 | DRD4 (1.00) | DRD4DRD2DRD3HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL29608988 | 0.75 | KMT2A (0.68) | DRD4DRD2DRD3HTR6BCHE | |
| SCHEMBL4077457 | 0.75 | DRD2 (0.59) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960101-A1 | 4-AMINOETHOXYINDAZOLE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-01 | — | — | EP | claimed |
| WO-1998035942-A1 | 4-AMINOETHOXYINDAZOLE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-08-20 | — | — | WO | claimed |
| WO-1998035943-A1 | 4-AMINOETHOXYINDAZOLE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-08-20 | — | — | WO | claimed |
| EP-0960101-A1 | 4-AMINOETHOXYINDAZOLE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998035942-A1 | 4-AMINOETHOXYINDAZOLE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |
| WO-1998035943-A1 | 4-AMINOETHOXYINDAZOLE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |