Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.32 |
| ▸ | BCAT1 | P54687 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616942 | 0.84 | TP53 (0.32) | TP53HTT | |
| SCHEMBL8612939 | 0.75 | NOTUM (0.32) | TP53HTTLMNANOTUM | |
| SCHEMBL8612848 | 0.75 | TP53 (0.34) | TP53HTTBCAT2BCAT1KDM4E | |
| SCHEMBL7752603 | 0.72 | MEN1 (0.31) | KMT2AAR | |
| SCHEMBL9221707 | 0.72 | ATM (0.52) | TP53KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL8761114 | 0.71 | NOTUM (0.34) | TP53HTTALDH1A1SMN1; SMN2NOTUM | |
| SCHEMBL7141262 | 0.70 | KDM4E (0.31) | TP53KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8173603 | 0.69 | RXFP1 (0.31) | — | |
| SCHEMBL8173601 | 0.68 | — | — | |
| SCHEMBL6983998 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836594-A1 | BENZYLHYDROXYLAMINES AND INTERMEDIATES USED TO PREPARE THEM | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-22 | — | — | EP | disclosed |