Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761988 | 0.88 | NOTUM (0.31) | NOTUMTP53HTT | |
| SCHEMBL8762288 | 0.83 | LMNA (0.33) | — | |
| SCHEMBL8612848 | 0.79 | TP53 (0.34) | NOTUMTP53HTTALDH1A1L3MBTL1 | |
| SCHEMBL8762018 | 0.75 | KDM4E (0.36) | NOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL8612939 | 0.73 | NOTUM (0.32) | NOTUMTP53HTT | |
| SCHEMBL7927759 | 0.72 | BCAT1 (0.42) | NOTUMHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7530294 | 0.72 | NOTUM (0.33) | NOTUM | |
| SCHEMBL7927757 | 0.72 | BCAT1 (0.42) | NOTUMHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7530298 | 0.72 | NOTUM (0.33) | NOTUM | |
| SCHEMBL7930382 | 0.71 | BCAT1 (0.42) | HTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770067-A1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996002518-A1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |