SCHEMBL8612233

SCHEMBL8612233

CC(C)CC(C)[CH]C(C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232674 0.73 TSHR (0.30) TSHR
SCHEMBL472838 0.69 TSHR (0.32) TSHR
SCHEMBL1717671 0.67 TSHR (0.39) ALDH1A1TSHRMAPK1
SCHEMBL233065 0.65
SCHEMBL5024767 0.63
SCHEMBL23567445 0.63
SCHEMBL7863812 0.63
SCHEMBL7870996 0.63
SCHEMBL12216596 0.63
SCHEMBL30481779 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-07-04 US disclosed
US-20230125359-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-04-27 US disclosed
US-11560383-B2 Compound and polymer compound containing the compound JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-01-24 US disclosed
EP-3763714-A1 COMPOUND AND POLYMERIC COMPOUND INCLUDING SAID COMPOUND Japan Science and Technology Agency (JP) 2021-01-13 EP disclosed
US-20210002284-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2021-01-07 US disclosed
US-5840722-A ADMINISTERING TO INHIBIT ENDOTHELIN RECEPTORS BASF AKTIENGESELLSCHAFT (DE) 1998-11-24 US disclosed
EP-0380985-B1 Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use BASF AG (DE) 1993-12-08 EP disclosed
EP-0380985-A2 Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use BASF Aktiengesellschaft (DE) 1990-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11560383-B2 Compound and polymer compound containing the compound RAD51, MDM2, UBE2D3 ALDH1A1 2360/4885TSHR 3330/4885MAPK1 3066/4885
US-20230125359-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, UBE2D3, MDM2 ALDH1A1 2249/4885TSHR 3539/4885MAPK1 3363/4885
US-20240217976-A2 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, MDM2, UBE2D3 ALDH1A1 2389/4885TSHR 3310/4885MAPK1 3098/4885
US-20210002284-A1 COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND RAD51, MDM2, UBE2D3 ALDH1A1 2360/4885TSHR 3330/4885MAPK1 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.