Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617020 | 1.00 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL8612467 | 1.00 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL8613509 | 1.00 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL8619087 | 1.00 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL1352227 | 1.00 | TSHR (0.42) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL8616905 | 0.98 | TSHR (0.40) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL8615910 | 0.91 | TSHR (0.38) | TSHRUSP2MAPTKDM4ETDP1 | |
| SCHEMBL8562549 | 0.84 | ACLY (0.42) | TSHRKDM4ETDP1ACLYCYP2C19 | |
| SCHEMBL8563267 | 0.84 | ACLY (0.42) | TSHRKDM4ETDP1ACLYCYP2C19 | |
| SCHEMBL11227427 | 0.82 | ACLY (0.44) | TSHRKDM4ETDP1ACLYCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837085-A1 | POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1998-04-22 | — | — | EP | disclosed |