SCHEMBL8563267

SCHEMBL8563267

O=C(O)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACLY P53396 3/20 0.42
ALDH1A1 P00352 1/20 0.39
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
CYP2C19 P33261 2/20 0.38
HIF1A Q16665 2/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.36
CPT2 P23786 2/20 0.33
KDM4E B2RXH2 1/20 0.33
FFAR1 O14842 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8562549 1.00 ACLY (0.42) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL11227427 0.97 ACLY (0.44) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL3862118 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL8618188 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL8618888 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL8614474 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL3864225 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL3863734 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
SCHEMBL3858790 0.92 THRB (0.48) ACLYALDH1A1HMGCRCHRM1TBXA2R
Ammonia Solution, Strong SCHEMBL27987372 0.90 THRB (0.46) ACLYALDH1A1HMGCRCHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750747-A FLUORINATED AMINE SALT COMPOUND HITACHI MAXELL, LTD. (JP) 1998-05-12 US disclosed