Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1426634 | 0.87 | TSHR (0.42) | TSHRTHRB | |
| SCHEMBL1044532 | 0.86 | TSHR (0.44) | TSHRTHRB | |
| Bromide SCHEMBL28722147 | 0.84 | TSHR (0.42) | TSHRTHRB | |
| SCHEMBL27591592 | 0.76 | TSHR (0.37) | TSHR | |
| Hydrochloric Acid SCHEMBL27544507 | 0.75 | TSHR (0.36) | TSHRTHRB | |
| Hydrochloric Acid SCHEMBL28719893 | 0.74 | TSHR (0.41) | TSHRTHRB | |
| Hydrochloric Acid SCHEMBL27548099 | 0.73 | TSHR (0.38) | TSHR | |
| Hydrochloric Acid SCHEMBL28053346 | 0.73 | TSHR (0.41) | TSHRTHRB | |
| Hydrochloric Acid SCHEMBL8336554 | 0.73 | TSHR (0.41) | TSHRTHRB | |
| SCHEMBL27533620 | 0.72 | TSHR (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886519-A1 | SUSTAINED RELEASE FORMULATION CONTAINING DFMO | Ilex Oncology, Inc. (US) | 1998-12-30 | — | — | EP | disclosed |
| WO-1998019667-A1 | SUSTAINED RELEASE FORMULATION CONTAINING DFMO | ILEX ONCOLOGY, INC. (US) | 1998-05-14 | — | — | WO | disclosed |