Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921620 | 0.93 | TP53 (0.61) | KMT2ASMN1; SMN2ESR1TP53TSHR | |
| SCHEMBL27486854 | 0.93 | TP53 (0.61) | KMT2ASMN1; SMN2ESR1TP53TSHR | |
| SCHEMBL10407329 | 0.89 | KMT2A (0.65) | KMT2ASMN1; SMN2ESR1LMNANPC1 | |
| SCHEMBL10540387 | 0.89 | RARB (0.64) | KMT2ASMN1; SMN2ESR1TP53TSHR | |
| SCHEMBL7484158 | 0.88 | BCL9 (0.58) | L3MBTL1KMT2AESR1TP53TSHR | |
| SCHEMBL27524018 | 0.88 | BCL9 (0.58) | L3MBTL1KMT2AESR1TSHRLMNA | |
| SCHEMBL15549028 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1LMNANPC1 | |
| SCHEMBL5696854 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1LMNANPC1 | |
| SCHEMBL38661498 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1LMNANPC1 | |
| SCHEMBL5696715 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2ESR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747537-A | Method of inhibiting parasitic activity | WASHINGTON UNIVERSITY (US) | 1998-05-05 | — | — | US | disclosed |