Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612914 | 0.91 | ALOX5 (0.44) | GSTP1MCL1ALOX5MAOBMAPT | |
| SCHEMBL8616628 | 0.90 | GSTP1 (0.45) | GSTP1ALOX5PTPN1MAOBMAOA | |
| SCHEMBL8616606 | 0.90 | GSTP1 (0.51) | GSTP1MCL1ALOX5PTPN1LMNA | |
| SCHEMBL8612910 | 0.90 | ALOX5 (0.50) | GSTP1ALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL8612316 | 0.90 | ALOX5 (0.50) | GSTP1ALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL8613858 | 0.88 | GSTP1 (0.54) | GSTP1ALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL8614632 | 0.88 | GSTP1 (0.54) | GSTP1MCL1LMNACYP1A2PTGS1 | |
| SCHEMBL8617918 | 0.88 | ERN1 (0.46) | RAB9ASMN1; SMN2 | |
| SCHEMBL8616652 | 0.87 | GSTP1 (0.50) | GSTP1MCL1ALOX5PTGER4PTGER3 | |
| SCHEMBL8612967 | 0.87 | GSTP1 (0.55) | GSTP1LMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |