Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 12/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613655 | 0.85 | ABCB1 (0.50) | ABCC9ABCB1 | |
| SCHEMBL9221558 | 0.81 | ABCB1 (0.56) | ABCC9ABCB1 | |
| SCHEMBL8612409 | 0.79 | ABCB1 (0.72) | ABCC9ABCB1 | |
| SCHEMBL27424805 | 0.79 | ABCB1 (0.72) | ABCC9ABCB1 | |
| SCHEMBL8612595 | 0.74 | ABCB1 (0.49) | ABCC9ABCB1 | |
| SCHEMBL9197746 | 0.73 | ABCC9 (0.68) | ABCC9ABCB1 | |
| SCHEMBL9197751 | 0.73 | ABCC9 (0.68) | ABCC9ABCB1 | |
| SCHEMBL9197759 | 0.73 | ABCC9 (0.68) | ABCC9ABCB1 | |
| SCHEMBL11027376 | 0.72 | ABCB1 (0.70) | ABCC9ABCB1 | |
| SCHEMBL10507344 | 0.72 | ABCB1 (0.70) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | claimed |
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | disclosed |