SCHEMBL861257

SCHEMBL861257

CC(C)(C)Cc1nc([N+](=O)[O-])c(Br)n1CC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.42
HTT P42858 6/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 3/20 0.38
JAK2 O60674 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HKDC1 Q2TB90 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 3/20 0.37
ALDH1A1 P00352 2/20 0.35
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861476 0.81 MAPT (0.57) MAPTHTTPOLBNPSR1JAK2
SCHEMBL3192831 0.66 MAPT (0.61) MAPTHTTPOLBNPSR1JAK2
SCHEMBL11870529 0.66 MAPT (0.40) MAPTHTTPOLBNPSR1JAK2
SCHEMBL11868445 0.65 MAPT (0.42) MAPTHTTPOLBNPSR1JAK2
SCHEMBL58073 0.64 MAPT (0.51) MAPTHTTPOLBNPSR1JAK2
SCHEMBL11860841 0.64 MAPT (0.38) MAPTHTTPOLBNPSR1JAK2
SCHEMBL4189866 0.61 MAPT (0.46) MAPTHTTPOLBNPSR1JAK2
SCHEMBL31144987 0.60 MAPT (0.41) MAPTHTTPOLBNPSR1JAK2
SCHEMBL29118210 0.60 CSNK2A2 (0.42) MAPTHTTPOLBNPSR1JAK2
SCHEMBL8340603 0.59 MAPT (0.50) MAPTHTTPOLBNPSR1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C MAPT 996/4885HTT 3124/4885POLB 2770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.