Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754375 | 0.85 | IGF1R (0.55) | CYP2D6MEN1KMT2AIGF1RLMNA | |
| SCHEMBL7754377 | 0.84 | CYP2D6 (0.48) | CYP2D6MEN1KMT2ALMNAADORA3 | |
| Hydrochloric Acid SCHEMBL7548578 | 0.84 | IGF1R (0.54) | CYP2D6MEN1KMT2AIGF1RLMNA | |
| SCHEMBL7446980 | 0.81 | IGF1R (0.56) | CYP2D6MEN1KMT2AIGF1RLMNA | |
| SCHEMBL9416450 | 0.81 | CYP2D6 (0.46) | CYP2D6MEN1KMT2ALMNAADORA3 | |
| SCHEMBL9145573 | 0.80 | MAPT (0.56) | CYP2D6MEN1KMT2AIGF1RMC4R | |
| SCHEMBL7435733 | 0.80 | IGF1R (0.60) | CYP2D6MEN1KMT2AIGF1RLMNA | |
| SCHEMBL7439416 | 0.77 | IGF1R (0.57) | CYP2D6MEN1KMT2AIGF1RLMNA | |
| SCHEMBL14355260 | 0.77 | IGF1R (0.60) | CYP2D6MEN1KMT2AIGF1RLMNA | |
| SCHEMBL9572466 | 0.77 | MAPT (0.60) | CYP2D6MEN1KMT2AIGF1RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549796-B1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEM IND INC (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0549796-A1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES INC (JP) | 1993-07-07 | — | — | EP | disclosed |