Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611050 | 0.81 | PDK2 (0.33) | PDK2 | |
| SCHEMBL8611462 | 0.66 | TP53 (0.52) | — | |
| SCHEMBL14604156 | 0.65 | APP (0.43) | — | |
| SCHEMBL8609115 | 0.64 | — | — | |
| SCHEMBL15710320 | 0.64 | ALDH1A1 (0.43) | — | |
| SCHEMBL18686113 | 0.64 | APP (0.42) | L3MBTL1 | |
| SCHEMBL31442138 | 0.63 | HDAC9 (0.35) | PARP1 | |
| SCHEMBL31011000 | 0.63 | MAPT (0.41) | PTGS2SIGMAR1L3MBTL1 | |
| SCHEMBL31010998 | 0.63 | MAPT (0.41) | PTGS2SIGMAR1L3MBTL1 | |
| SCHEMBL31010999 | 0.63 | MAPT (0.41) | PTGS2SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |