SCHEMBL861270

SCHEMBL861270

C=CC(O)N1CCNCC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2D6 P10635 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10832743 1.00 MEN1 (0.33) MEN1KMT2ACYP2D6CYP19A1
SCHEMBL7135901 0.98 MEN1 (0.32) MEN1KMT2ACYP2D6CYP19A1
SCHEMBL11249601 0.92 SLC6A2 (0.31)
SCHEMBL10529822 0.86
SCHEMBL7680456 0.82
SCHEMBL1072391 0.82
SCHEMBL2204103 0.77
SCHEMBL5994292 0.76 MEN1 (0.31) MEN1KMT2A
SCHEMBL28601553 0.75 LMNA (0.38) KMT2A
SCHEMBL19559990 0.75 FDPS (0.36) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114062091-B Method for detecting hydroxyalkyl piperazine in flue gas desulfurizing agent 安徽大学 2023-09-01 CN claimed
CN-114870569-B Synthetic method of piperazine-based carbon trapping agent 合肥工业大学 2023-04-07 CN claimed
CN-114870569-A Synthetic method of piperazine-based carbon trapping agent 合肥工业大学 2022-08-09 CN claimed
CN-114699900-A Preparation method and application of hydroxyalkyl piperazine-based carbon trapping agent 合肥工业大学 2022-07-05 CN claimed
CN-107848993-B Process for producing hydroxyethylpiperazine compound 陶氏环球技术有限责任公司 2022-03-08 CN claimed
CN-114062091-A Method for detecting hydroxyalkyl piperazine in flue gas desulfurizing agent 安徽大学 2022-02-18 CN claimed
CN-112973419-A Proportion-controllable composite hydroxyalkyl piperazine desulfurizer as well as preparation method and application thereof 合肥工业大学 2021-06-18 CN claimed
CN-111905523-A Composition for removing sulfur dioxide from flue gas, preparation method thereof and flue gas desulfurization method 攀钢集团研究院有限公司 2020-11-10 CN claimed
CN-111905524-A Flue gas desulfurizing agent, preparation method thereof and flue gas desulfurizing method 攀钢集团研究院有限公司 2020-11-10 CN claimed
US-10626097-B2 Process for making hydroxyethyl piperazine compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2020-04-21 US claimed
EP-0189078-B1 TRICYCLIC COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND METHOD OF TREATMENT THEREWITH AB LEO (SE) 1989-06-28 EP claimed
US-4791043-A N-AMINOALKYLPIPERAZINES, N-HYDROXYALKYLPIPERAZINES, 2-PYRROLIDONES HMC PATENTS HOLDING CO., INC. (US) 1988-12-13 US claimed
EP-0106860-B1 NEW CARBOXAMIDOGUANIDINS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOUCHARA S.A. (FR) 1988-01-20 EP claimed
US-4709034-A ALKYLENE GLYCOL AND AMMONIA OR ALKYL AMINE; TRANSITION METAL CARBONYL COMPLEX CATALYST PRECURSOR AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-11-24 US claimed
EP-0234401-A1 Process for the synthesis of hydroxyalkyl amines and hydroxyalkyl piperazines AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-09-02 EP claimed
US-4645758-A Urinary incontinence ameliorating dibenz- b,e- -oxepin and -thiepin derivatives, compositions, and method of use therefor AKTIEBOLAGET LEO (SE) 1987-02-24 US claimed
EP-0189078-A1 Tricyclic compounds, compositions containing such compounds, processes for their preparation and method of treatment therewith AB LEO (SE) 1986-07-30 EP claimed
EP-0145973-A2 Positive photoresist stripping composition HMC Patents Holding Co., Inc. (US) 1985-06-26 EP claimed
EP-0048985-A1 Process for cellular polyurethane formation using tertiary amine catalyst mixtures UNION CARBIDE CORPORATION (US) 1982-04-07 EP claimed
US-4235730-A DISPERSANTS TEXACO INC. (US) 1980-11-25 US claimed