Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1669211 | 0.85 | MEN1 (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL28399523 | 0.85 | MEN1 (0.41) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL8406803 | 0.83 | ERN1 (0.48) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL2179847 | 0.83 | LIPG (0.42) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL29897321 | 0.82 | LMNA (0.57) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL224815 | 0.82 | LMNA (0.57) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL198461 | 0.82 | CSNK2A2 (0.52) | LMNAALDH1A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL249552 | 0.82 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL31175932 | 0.82 | KMT2A (0.71) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL2223292 | 0.82 | LMNA (0.46) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1708491-A | N-benzodioxolyl, N-benzodioxanyl and N-benzodioxepinyl arylcarbonxamide derivatives, and pharmaceutical compositions comprising them | MERCK PATENT GMBH (DE) | 2005-12-14 | — | — | CN | disclosed |
| EP-0150908-B1 | Use of Curable impregnant compositions for impregnating electrical appliances | NIPPON PETROCHEMICALS CO LTD (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-4670348-A | Electrical appliance impregnated with a curable impregnant composition | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1987-06-02 | — | — | US | disclosed |
| EP-0150908-A1 | Use of Curable impregnant compositions for impregnating electrical appliances | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1985-08-07 | — | — | EP | disclosed |