SCHEMBL8612832

SCHEMBL8612832

OC(C(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8618002 1.00 LMNA (0.33) LMNATHRB
SCHEMBL8617319 1.00 LMNA (0.33) LMNATHRB
SCHEMBL9488923 1.00 LMNA (0.33) LMNATHRB
SCHEMBL8612586 0.77 CETP (0.30)
SCHEMBL10701466 0.77 THRB (0.32) LMNATHRB
SCHEMBL8614174 0.75 LMNA (0.38) LMNATHRB
SCHEMBL8615905 0.75 LMNA (0.38) LMNATHRB
SCHEMBL8618276 0.75 LMNA (0.38) LMNATHRB
SCHEMBL8614205 0.75 LMNA (0.38) LMNATHRB
SCHEMBL8618828 0.75 LMNA (0.38) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed