Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588129 | 0.87 | EPHX2 (0.44) | PPARGEPHX2 | |
| SCHEMBL8589579 | 0.83 | KMT2A (0.50) | PPARGPPARAALDH1A1ATMLMNA | |
| SCHEMBL8590699 | 0.82 | MC5R (0.42) | PPARGEPHX2MAOBKDM4EALDH1A1 | |
| SCHEMBL8586939 | 0.82 | LMNA (0.52) | LMNA | |
| SCHEMBL8588116 | 0.79 | CYP1A2 (0.42) | ALDH1A1 | |
| SCHEMBL8587466 | 0.79 | KCNH2 (0.56) | PPARGPPARACNR2CNR1ALDH1A1 | |
| SCHEMBL8587877 | 0.78 | ACP3 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL8585890 | 0.78 | DPP7 (0.53) | ATM | |
| SCHEMBL8588727 | 0.77 | SLC6A4 (0.48) | — | |
| SCHEMBL8588991 | 0.77 | KMT2A (0.39) | MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |