Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612841 | 0.87 | PPARG (0.42) | EPHX2PPARG | |
| SCHEMBL8588989 | 0.83 | CYP19A1 (0.43) | MME | |
| SCHEMBL8590699 | 0.82 | MC5R (0.42) | EPHX2PPARG | |
| SCHEMBL8589507 | 0.82 | KIF11 (0.49) | EPHX2MME | |
| SCHEMBL8588155 | 0.80 | LMNA (0.57) | MME | |
| SCHEMBL8588116 | 0.79 | CYP1A2 (0.42) | — | |
| SCHEMBL8588435 | 0.79 | SIGMAR1 (0.51) | — | |
| SCHEMBL8590681 | 0.77 | ATM (0.51) | — | |
| SCHEMBL8588991 | 0.77 | KMT2A (0.39) | — | |
| SCHEMBL8589191 | 0.77 | ALDH1A1 (0.43) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |