Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590339 | 0.74 | LMNA (0.34) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL9117495 | 0.72 | CA12 (0.50) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL28356736 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL28356435 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL28352617 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL25211225 | 0.71 | CA12 (0.49) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL6349798 | 0.70 | LMNA (0.39) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL16319226 | 0.70 | CA12 (0.54) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL3835020 | 0.70 | LMNA (0.43) | LMNATHRBCYP2C19CYP3A4CYP2D6 | |
| SCHEMBL8741557 | 0.70 | LMNA (0.43) | LMNATHRBCYP2C19CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050421-A1 | ANALGESIC PEPTIDOMIMETIC COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-11-12 | — | — | WO | disclosed |