Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28352617 | 0.99 | CA12 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28356736 | 0.99 | CA12 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL25211225 | 0.99 | CA12 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL28356435 | 0.99 | CA12 (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL16319226 | 0.89 | CA12 (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL13941939 | 0.82 | CA12 (0.50) | CA12CA1CA2CA9LMNA | |
| SCHEMBL12391050 | 0.81 | LMNA (0.57) | CA12CA1CA2CA9LMNA | |
| SCHEMBL17783193 | 0.81 | LMNA (0.54) | CA12CA1CA2CA9LMNA | |
| SCHEMBL11390072 | 0.81 | CA12 (0.64) | CA12CA1CA2CA9LMNA | |
| SCHEMBL25207398 | 0.80 | MITF (0.48) | CA12CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7033745-A | — | — | None | — | — | JP | disclosed |
| JP-H0733745-A | 2-NITROIMIDAZOLE COMPOUNDS | TAIHO YAKUHIN KOGYO KK | 1995-02-03 | — | — | JP | disclosed |