SCHEMBL86130

SCHEMBL86130

COC(=O)c1cc2c(cc1C(=O)OC)C1(c3ccccc3)OOC2(c2ccccc2)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 5/20 0.40
CFTR P13569 2/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 4/20 0.40
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 5/20 0.39
HPGD P15428 4/20 0.39
GOPC Q9HD26 1/20 0.39
POLB P06746 1/20 0.39
ATM Q13315 1/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
PDK2 Q15119 3/20 0.39
GPR55 Q9Y2T6 1/20 0.39
GAA P10253 1/20 0.38
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30463421 0.74 CFTR (0.50) TSHRLMNAALDH1A1CFTRHSD17B10
SCHEMBL4143463 0.74 CFTR (0.50) TSHRLMNAALDH1A1CFTRHSD17B10
SCHEMBL28765854 0.69 LMNA (0.44) TSHRLMNAALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL27438615 0.68 TSHR (0.71) TSHRLMNAALDH1A1CFTRHSD17B10
SCHEMBL29438041 0.67 KDM4E (0.61) TSHRLMNAALDH1A1CFTRHSD17B10
SCHEMBL68218 0.67 KDM4E (0.61) TSHRLMNAALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL28258660 0.66 TSHR (0.68) TSHRLMNAALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL790124 0.66 TSHR (0.74) TSHRLMNAALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL29500970 0.66 TSHR (0.74) TSHRLMNAALDH1A1CFTRHSD17B10
Dimethyl Phthalate SCHEMBL34630 0.66 TSHR (0.74) TSHRLMNAALDH1A1CFTRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8298976-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-10-30 US disclosed
US-8216969-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-07-10 US disclosed
US-8129303-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-03-06 US disclosed
US-8114810-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2012-02-14 US disclosed
US-8058206-B2 Pathogen-resistant fabrics U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2011-11-15 US disclosed
US-8058207-B2 Pathogen-resistant fabrics LOMBARDI JOHN L (US) 2011-11-15 US disclosed
US-20110250424-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-10-13 US disclosed
US-20110184164-A1 Pathogen-Resistant Fabrics U.S. GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY 2011-07-28 US disclosed
US-20110183569-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-07-28 US disclosed
US-20110183571-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-07-28 US disclosed
US-20110183572-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-07-28 US disclosed
US-20110183570-A1 Pathogen-Resistant Fabrics LOMBARDI JOHN L 2011-07-28 US disclosed
US-7915197-B2 Photocatalyst capable of generating singlet oxygen from ambient air in polymeric material; protection from toxic chemical and biological agents (\"CBAs\"); emergency medical or military use such as body bags, protective clothing, shelters LOMBARDI JOHN L 2011-03-29 US disclosed
US-7642215-B2 Chemically-resistant shelter coatings LOMBARDI JOHN 2010-01-05 US disclosed
US-20080171803-A1 Pathogen-resistant coatings LOMBARDI JOHN L 2008-07-17 US disclosed
US-20080153690-A1 CHEMICALLY-RESISTANT SHELTER COATINGS LOMBARDI JOHN L 2008-06-26 US disclosed
US-7259122-B1 Chemically-resistant shelter coating LOMBARDI JOHN 2007-08-21 US disclosed