Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8615965 | 0.98 | PGR (0.35) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL16852139 | 0.82 | GABRR1 (0.34) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL4595832 | 0.80 | CHRNB2 (0.35) | CA1CA2DPP4DPP8DPP9 | |
| SCHEMBL23205719 | 0.80 | HTR2A (0.41) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL23174419 | 0.80 | HTR2A (0.41) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL23174418 | 0.80 | HTR2A (0.41) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL23174420 | 0.80 | HTR2A (0.41) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL19293124 | 0.80 | CHRNB2 (0.35) | CA1CA2DPP4DPP8DPP9 | |
| SCHEMBL18928722 | 0.80 | CHRNB2 (0.35) | CA1CA2DPP4DPP8DPP9 | |
| SCHEMBL4595828 | 0.80 | CHRNB2 (0.35) | CA1CA2DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |