Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341113 | 0.90 | CYP1A2 (0.38) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10340942 | 0.89 | KDM4E (0.42) | SMN1; SMN2HPGDALDH1A1LMNAMAPT | |
| SCHEMBL10341075 | 0.88 | ALDH1A1 (0.35) | SMN1; SMN2HPGDALDH1A1LMNAMAPT | |
| SCHEMBL9619631 | 0.87 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8613118 | 0.87 | CYP1A2 (0.35) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10340889 | 0.87 | ATM (0.38) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10340982 | 0.87 | LMNA (0.38) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10340906 | 0.86 | ATM (0.35) | SMN1; SMN2HPGDALDH1A1ATMRAB9A | |
| SCHEMBL10340941 | 0.86 | CYP1A2 (0.55) | SMN1; SMN2HPGDALDH1A1LMNAMAPT | |
| SCHEMBL10341084 | 0.85 | ALDH1A1 (0.34) | SMN1; SMN2HPGDALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750721-A | 1,3-dimethyl-5-fluoro-pyrazole-4-carbonyl fluoride | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |
| US-5675016-A | Process for the preparation of 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilides | BAYER AKTIENGESELLSCHAFT (DE) | 1997-10-07 | — | — | US | disclosed |
| EP-0199822-B1 | PYRAZOLECARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND BACTERICIDES CONTAINING THEM AS EFFECTIVE INGREDIENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4742074-A | Pyrazolecarboxamide derivative and fungicide containing it as active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0199822-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND BACTERICIDES CONTAINING THEM AS EFFECTIVE INGREDIENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-05 | — | — | EP | disclosed |