Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619427 | 0.89 | MCHR1 (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8617772 | 0.86 | RAB9A (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8614062 | 0.81 | SCN2A (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8613854 | 0.80 | SCN2A (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8616642 | 0.79 | KDM4E (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8613677 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8616496 | 0.79 | KDM4E (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8617935 | 0.79 | RAB9A (0.41) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8613484 | 0.79 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8615687 | 0.79 | RAB9A (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |