Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619427 | 0.88 | MCHR1 (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8612684 | 0.86 | CSF1R (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8619419 | 0.83 | SMO (0.38) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8617741 | 0.79 | SCN2A (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8614015 | 0.79 | ADRA2A (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8613223 | 0.79 | SMN1; SMN2 (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8614313 | 0.78 | RAB9A (0.39) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8620942 | 0.78 | HDAC6 (0.42) | ALDH1A1LMNAHPGDTSHRNPSR1 | |
| SCHEMBL8615213 | 0.78 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8615943 | 0.78 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |