SCHEMBL8613245

SCHEMBL8613245

CCc1cc(C2=Cc3ccccc3C2[Hf])c2ccccc2c1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8620251 0.88 PSMB5 (0.34) CYP1A2
Hydrochloric Acid SCHEMBL4078644 0.83 HTR6 (0.34) HTR6CYP1A2CYP2A6
SCHEMBL8617032 0.78 KDM4E (0.36) HTR6
Hydrochloric Acid SCHEMBL5612566 0.78 HTR6 (0.32) HTR6CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL7783023 0.72 PSMB5 (0.34) CYP1A2
Hydrochloric Acid SCHEMBL7807249 0.72 CYP1A2 (0.34) HTR6CYP1A2CYP2A6
SCHEMBL7202153 0.71 CYP1A2 (0.34) CYP1A2
SCHEMBL7800538 0.71 CYP1A2 (0.33) CYP1A2CYP2A6
SCHEMBL6758600 0.71 CYP1A2 (0.40) HTR6CYP1A2CYP2A6
SCHEMBL8615005 0.70 CNR2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0837866-A1 PROCESS FOR CONVERTING THE ACHIRAL MESO FORM OR THE RACEMATE OF AN ANSA-METALLOCENE COMPLEX OR MIXTURES THEREOF INTO ONE OF ITS ENANTIOMERS BASF AKTIENGESELLSCHAFT (DE) 1998-04-29 EP disclosed
WO-1997003081-A1 PROCESS FOR CONVERTING THE ACHIRAL MESO FORM OR THE RACEMATE OF AN ANSA-METALLOCENE COMPLEX OR MIXTURES THEREOF INTO ONE OF ITS ENANTIOMERS BASF AKTIENGESELLSCHAFT (DE) 1997-01-30 WO disclosed