Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7807249 | 0.88 | CYP1A2 (0.34) | HTR6CYP1A2CYP2A6 | |
| SCHEMBL8613245 | 0.83 | HTR6 (0.35) | HTR6CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL7196886 | 0.83 | CYP1A2 (0.40) | CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL5612566 | 0.80 | HTR6 (0.32) | HTR6CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL7807224 | 0.78 | PTPN1 (0.35) | CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL8169170 | 0.77 | PSMB5 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4078640 | 0.76 | CYP11B1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7807237 | 0.73 | CYP3A4 (0.30) | — | |
| SCHEMBL8620251 | 0.72 | PSMB5 (0.34) | CYP1A2 | |
| Hydrochloric Acid SCHEMBL7643736 | 0.71 | CYP1A2 (0.33) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205363-B2 | Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene | EXXON MOBIL CHEMICAL PATENTS INC. (US) | 2007-04-17 | — | — | US | claimed |
| US-20040254316-A1 | Polymerization processes using antistatic agents | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-16 | — | — | US | claimed |
| US-6667272-B2 | Metallocene, an activator and a fluorided support; use as alpha-olefin polymerization catalysts, polypropylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-12-23 | — | — | US | claimed |
| US-6664348-B2 | Metallocene catalyst such as dimethylsilandiylbis(2-ethyl-4-phenyl-1-indenyl)zirconium dimethyl for polymerization of propylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-12-16 | — | — | US | claimed |
| US-6524988-B2 | Metallocene, an activator and a fluorided support; polymerization catalyst | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-02-25 | — | — | US | claimed |
| US-20020160914-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-10-31 | — | — | US | claimed |
| US-20010051698-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-13 | — | — | US | claimed |
| US-7521507-B2 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-2045304-A2 | Polypropylene-Based Adhesive Compositions | ExxonMobil Chemical Patents Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| US-7205363-B2 | Using fluorided silica supported metallocene catalyst system and antistatic agent selected from polysulfone copolymer, polyamine, oil soluble sulfonic acid or mixture, for homo or copolymerization of propylene | EXXON MOBIL CHEMICAL PATENTS INC. (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1237957-B1 | PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS | EXXONMOBIL CHEM PATENTS INC (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20040254316-A1 | Polymerization processes using antistatic agents | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-16 | — | — | US | disclosed |
| US-20040110886-A1 | Polypropylene-based adhesive compositions | KARANDINOS ANTHONY GEORGE (BE) | 2004-06-10 | — | — | US | disclosed |
| EP-1237957-A1 | PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6395847-B2 | COMBINING NUCLEOPHILIC PARTICULATE SUPPORT WITH ARYLBORON OR ARYLALUMINUM LEWIS ACID COMPOUND IN PRESENCE OF LEWIS BASE; CONTACTING PRODUCT OF WITH TRIALKYLALUMINUM COMPOUND; AND, REACTING PRODUCT WITH METALLIC PRECURSOR | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-05-28 | — | — | US | disclosed |
| US-20020019507-A1 | Polypropylene-based adhesive compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-02-14 | — | — | US | disclosed |
| US-20010051698-A1 | Highly active supported catalyst compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-13 | — | — | US | disclosed |
| US-20010049331-A1 | SUPPORTED ORGANOMETALLIC CATALYSTS AND THEIR USE IN OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. | 2001-12-06 | — | — | US | disclosed |
| WO-2001036499-A1 | PREPARATION OF SUPPORTED POLYMERIZATION CATALYSTS | EXXON CHEMICAL PATENTS INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| CN-1246871-A | Propylene polymers incorporating polyethylene macromers | EXXON CHEMICAL PATENTS INC (US) | 2000-03-08 | — | — | CN | disclosed |