Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.59 |
| ▸ | QPCT | Q16769 | 1/20 | 0.48 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RAD1 | O60671 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614023 | 0.87 | ENPP2 (0.57) | ENPP2RAD51MAPTMEN1KMT2A | |
| SCHEMBL14361802 | 0.86 | ENPP2 (0.62) | ENPP2RAD51MAPTCYP1A2CYP3A4 | |
| SCHEMBL14361809 | 0.86 | ENPP2 (0.62) | ENPP2RAD51MAPTCYP1A2CYP3A4 | |
| SCHEMBL19726887 | 0.85 | ENPP2 (0.52) | ENPP2RAD51MAPTHTTL3MBTL1 | |
| SCHEMBL19726895 | 0.84 | ENPP2 (0.49) | ENPP2RAD51MAPTMEN1KMT2A | |
| SCHEMBL14361680 | 0.82 | ENPP2 (0.58) | ENPP2RAD51MAPTHTTL3MBTL1 | |
| SCHEMBL14361673 | 0.82 | ENPP2 (0.58) | ENPP2RAD51MAPTHTTL3MBTL1 | |
| SCHEMBL8613300 | 0.81 | ENPP2 (0.53) | ENPP2RAD51MAPTKMT2AGAA | |
| SCHEMBL8609894 | 0.81 | MAPT (0.47) | QPCTMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL14358754 | 0.80 | ENPP2 (0.74) | ENPP2RAD51MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626945-B1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMA INC (US) | 1998-04-22 | — | — | EP | claimed |
| EP-0626945-A1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1994-12-07 | — | — | EP | claimed |
| US-5359131-A | Sulfonic acid derivatives in the treatment of viral diseases | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-25 | — | — | US | claimed |
| WO-1993016992-A1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-02 | — | — | WO | claimed |
| EP-0626945-B1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMA INC (US) | 1998-04-22 | — | — | EP | disclosed |
| US-5359131-A | Sulfonic acid derivatives in the treatment of viral diseases | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-25 | — | — | US | disclosed |