Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAD1 | O60671 | 1/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614023 | 0.88 | ENPP2 (0.57) | ENPP2ALDH1A1MAPTCA1CA2 | |
| SCHEMBL8609312 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTNPSR1CA1CA2 | |
| SCHEMBL8613403 | 0.81 | ENPP2 (0.59) | ENPP2ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL14361809 | 0.81 | ENPP2 (0.62) | ENPP2ALDH1A1MAPTRAD1P2RY6 | |
| SCHEMBL14361802 | 0.81 | ENPP2 (0.62) | ENPP2ALDH1A1MAPTRAD1P2RY6 | |
| SCHEMBL10773614 | 0.81 | CHAT (0.48) | ENPP2CA1CA2CA9CA12 | |
| SCHEMBL10487283 | 0.81 | CHAT (0.48) | ENPP2CA1CA2CA9CA12 | |
| SCHEMBL10773637 | 0.81 | CHAT (0.48) | ENPP2CA1CA2CA9CA12 | |
| SCHEMBL9358989 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTNPSR1CA1CA2 | |
| SCHEMBL10487256 | 0.80 | CHAT (0.48) | ENPP2CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626945-B1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMA INC (US) | 1998-04-22 | — | — | EP | claimed |
| US-5359131-A | Sulfonic acid derivatives in the treatment of viral diseases | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-25 | — | — | US | claimed |
| EP-0626945-B1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMA INC (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0626945-A1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5359131-A | Sulfonic acid derivatives in the treatment of viral diseases | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1993016992-A1 | SULFONIC ACID DERIVATIVES IN THE TREATMENT OF VIRAL DISEASES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-02 | — | — | WO | disclosed |