Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837744 | 0.72 | — | — | |
| SCHEMBL3271093 | 0.70 | ADH1A (0.32) | — | |
| SCHEMBL3276795 | 0.68 | ADH1A (0.36) | — | |
| SCHEMBL18207894 | 0.67 | — | — | |
| SCHEMBL30980356 | 0.65 | — | — | |
| SCHEMBL9163158 | 0.63 | TRPV1 (0.30) | — | |
| SCHEMBL2700252 | 0.63 | S1PR4 (0.40) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL4259291 | 0.63 | S1PR4 (0.40) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6378870 | 0.63 | S1PR4 (0.35) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL19212002 | 0.62 | S1PR4 (0.42) | S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783602-A | Leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |
| EP-0741686-B1 | NEW LEUKOTRIENE B4 DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AG (DE) | 1998-04-22 | — | — | EP | disclosed |
| EP-0741686-A1 | NEW LEUKOTRIENE B 4? DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020562-A1 | LEUKOTRIENE B4 DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-03 | — | — | WO | disclosed |
| WO-1995020563-A1 | NEW LEUKOTRIENE B4 DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-03 | — | — | WO | disclosed |