Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | NAMPT | P43490 | 2/20 | 0.57 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 6/20 | 0.48 |
| ▸ | DRD3 | P35462 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8621873 | 0.99 | RAB9A (0.61) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL8966492 | 0.84 | RAB9A (0.62) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL8966338 | 0.83 | RAB9A (0.61) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL8620030 | 0.80 | RAB9A (0.60) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL8615161 | 0.79 | RAB9A (0.59) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL5094626 | 0.79 | RAB9A (0.77) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL8613372 | 0.78 | GAA (0.65) | RAB9AHDAC3HDAC1POLB | |
| SCHEMBL8899400 | 0.77 | RAB9A (1.00) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL1193044 | 0.77 | RAB9A (0.75) | RAB9ANAMPTACKR3HDAC3HDAC4 | |
| SCHEMBL444315 | 0.77 | RAB9A (0.60) | RAB9ANAMPTACKR3HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |