Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | DRD3 | P35462 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620030 | 0.97 | RAB9A (0.60) | RAB9ANAMPTACKR3DRD2DRD3 | |
| SCHEMBL8618591 | 0.92 | RAB9A (0.56) | RAB9ANAMPTACKR3DRD2DRD3 | |
| SCHEMBL8966304 | 0.83 | RAB9A (0.60) | RAB9ANAMPTACKR3DRD2DRD3 | |
| SCHEMBL8966996 | 0.80 | RAB9A (0.61) | RAB9ANAMPTACKR3DRD2DRD3 | |
| SCHEMBL8615169 | 0.80 | KDM4E (0.58) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL8618256 | 0.79 | SMN1; SMN2 (0.50) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL8613525 | 0.79 | RAB9A (0.62) | RAB9ANAMPTACKR3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8621873 | 0.78 | RAB9A (0.61) | RAB9ANAMPTACKR3DRD2DRD3 | |
| SCHEMBL8618595 | 0.78 | NPC1 (0.67) | RAB9AKMT2ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL8617641 | 0.78 | SMN1; SMN2 (0.63) | RAB9ANAMPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767121-A | ANTIINFLAMMATORY AND -ARTHRITIC AGENTS; ANTIPYRETICS; ANALGESICS; ADHESION PROTEIN EXPRESSION AND CYCLOXYGENASE AND 5-LIPOXYGENASE INHIBITORS; IMMUNOSUPPRESSANTS AND -MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-16 | — | — | US | disclosed |