Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914582 | 0.95 | SPR (0.57) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL5339923 | 0.86 | MTNR1A (0.71) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL8961211 | 0.86 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6076081 | 0.85 | MTNR1A (0.57) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL6077106 | 0.85 | MTNR1A (0.60) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL8961300 | 0.81 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6075543 | 0.81 | MTNR1A (0.54) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL5346620 | 0.81 | MTNR1A (0.72) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL8609306 | 0.81 | MTNR1A (0.72) | SPRMTNR1AMTNR1BNQO2 | |
| SCHEMBL6076229 | 0.79 | MTNR1A (0.52) | SPRMTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662471-B1 | Naphthalene derivatives with affinity to the receptors of melatonine, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-03-11 | — | — | EP | disclosed |
| US-5591775-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-01-07 | — | — | US | disclosed |
| US-5552418-A | FOR TREATING DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1996-09-03 | — | — | US | disclosed |
| EP-0662471-A2 | Naphthalene derivatives with affinity to the receptors of melatonine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-07-12 | — | — | EP | disclosed |