Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 10/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618306 | 0.86 | NR3C1 (0.45) | TBXA2RTBXAS1NR3C1 | |
| SCHEMBL6938853 | 0.78 | TBXA2R (0.45) | TBXA2RTBXAS1CYP19A1 | |
| SCHEMBL8617506 | 0.76 | TBXA2R (0.46) | TBXA2RTBXAS1 | |
| SCHEMBL9063943 | 0.76 | TBXA2R (0.41) | TBXA2RCYP19A1 | |
| SCHEMBL7509159 | 0.76 | TBXA2R (0.41) | TBXA2RCYP19A1 | |
| SCHEMBL8797713 | 0.74 | TBXA2R (0.44) | TBXA2RTBXAS1 | |
| SCHEMBL12205621 | 0.74 | ACP3 (0.44) | NR3C1 | |
| SCHEMBL12205541 | 0.74 | HDAC4 (0.46) | NR3C1 | |
| SCHEMBL8797524 | 0.73 | TP53 (0.40) | TBXA2RTBXAS1 | |
| SCHEMBL9331532 | 0.72 | TBXA2R (0.39) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-B1 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |