Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 5/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615719 | 0.83 | TBXAS1 (0.41) | TBXA2RTBXAS1MAPTTP53ATM | |
| SCHEMBL8613749 | 0.82 | LPAR1 (0.45) | TBXA2RTBXAS1 | |
| SCHEMBL8616314 | 0.81 | TBXA2R (0.39) | TBXA2RTBXAS1MAPTTP53TSHR | |
| SCHEMBL9331532 | 0.81 | TBXA2R (0.39) | TBXA2RTBXAS1MAPTTP53SHMT2 | |
| SCHEMBL8615128 | 0.79 | LPAR1 (0.48) | — | |
| SCHEMBL8620383 | 0.77 | TBXAS1 (0.43) | TBXA2RTBXAS1MAPTTP53GAA | |
| SCHEMBL8620512 | 0.76 | RAB9A (0.41) | TBXAS1MAPTTP53KMT2ATSHR | |
| SCHEMBL8617043 | 0.73 | TBXA2R (0.39) | TBXA2RTBXAS1MAPTTP53KMT2A | |
| SCHEMBL9329616 | 0.73 | TBXAS1 (0.42) | TBXA2RTBXAS1MAPTTP53 | |
| SCHEMBL8614659 | 0.72 | TBXAS1 (0.39) | TBXA2RTBXAS1TP53KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588608-B1 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO KK (JP) | 1998-05-06 | — | — | EP | disclosed |
| EP-0588608-A2 | Tricyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |