Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132797 | 0.67 | ALDH1A1 (0.36) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL1686188 | 0.63 | ALDH1A1 (0.33) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29275506 | 0.62 | MEN1 (0.41) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL10648071 | 0.60 | ALDH1A1 (0.48) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24220059 | 0.60 | ALDH1A1 (0.41) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL18382542 | 0.60 | — | — | |
| SCHEMBL4157000 | 0.60 | LMNA (0.60) | KDM4EALDH1A1HTTCYP1A2LMNA | |
| SCHEMBL4157002 | 0.60 | LMNA (0.60) | KDM4EALDH1A1HTTCYP1A2LMNA | |
| SCHEMBL16175866 | 0.59 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL16850624 | 0.59 | KDM4E (0.68) | KDM4EALDH1A1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472234-B1 | QUINAZOLINONE DERIVATIVES AND THEIR USE AS CB AGONISTS | NOVARTIS AG (CH) | 2012-03-28 | — | — | EP | disclosed |